BDBM50238733 CHEMBL4099302

SMILES CN(CCO)C(=O)C=Cc1ccc(cc1)C(=C1C2CC3CC(C2)CC1C3)c1ccc(O)cc1

InChI Key InChIKey=FDMWPPUFQNIOPL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238733   

TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238733(CHEMBL4099302)
Affinity DataIC50: 5.40nMAssay Description:Downregulation of human ERalpha in human MCF-7 cells after 24 hrs by in-cell Western immunoassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238733(CHEMBL4099302)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed