BDBM50238385 CHEMBL260546::N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-tolyloxy)acetamide

SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N

InChI Key InChIKey=IYCJSGBIJLZWDK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238385   

TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238385(N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-toly...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CETP assessed as cholesteryl ester transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238385(N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-toly...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CETP in human whole plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238385(N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-toly...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCholine/ethanolaminephosphotransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238385(N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-toly...)
Affinity DataIC50: 130nMAssay Description:inhibition of human CEPT assessed as cholesteryl ester transfer by fluorescence transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed