BDBM50238247 CHEMBL4081888

SMILES [H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(C)=O)c2ccccc12

InChI Key InChIKey=UOSLBPLDOIRCLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238247   

TargetComplement factor D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50238247(CHEMBL4081888)
Affinity DataIC50: 35nMAssay Description:Inhibition of complement factor D in human whole blood assessed as decrease in zymosan-induced AP activation mediated soluble MAC complex formation p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement factor D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50238247(CHEMBL4081888)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed