BDBM50237832 CHEMBL1198335

SMILES COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1

InChI Key InChIKey=FBWZAFQEOKNGQL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237832   

TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237832(CHEMBL1198335)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of myc-tagged PAK4 (unknown origin) using histone H3 as substrate preincubated for 30 mins followed by substrate addition measured for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237832(CHEMBL1198335)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of PAK4 (unknown origin) using histone H3 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237832(CHEMBL1198335)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237832(CHEMBL1198335)
Affinity DataIC50: 15nMAssay Description:Inhibition of PAK4 (unknown origin) assessed as reduction in histone phosphorylation incubated for 1 hr at 4 degC by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237832(CHEMBL1198335)
Affinity DataIC50: 48nMAssay Description:Inhibition of PAK1 (unknown origin) assessed as reduction in histone phosphorylation incubated for 1 hr at 4 degC by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed