BDBM50237802 CHEMBL4062769

SMILES COc1cnc-2c(c1)C(=O)c1c-2n(CCCN2CCN(C)CC2)c(=O)c2cc(ccc12)[N+]([O-])=O

InChI Key InChIKey=INJUSSRMORXZTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237802   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50237802(CHEMBL4062769)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) assessed as decrease in hydrolysis of phosphodiester linkage between tyrosine residue and the 3' end ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50237802(CHEMBL4062769)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human Tdp2 assessed as decrease in alpha 32P-cordycepin-3'-labeled DNA breaks after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2019
Entry Details Article
PubMed