BDBM50237793 CHEMBL4070352

SMILES COc1cccc(N\C(NCC23CC4CC(CC(C4)C2)C3)=N\C#N)c1

InChI Key InChIKey=BKZLASBRTMKYQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237793   

TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237793(CHEMBL4070352)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2019
Entry Details Article
PubMed