BDBM50237730 CHEMBL4074449

SMILES N#C\N=C(/NCC12CC3CC(CC(C3)C1)C2)Nc1cccc2ncccc12

InChI Key InChIKey=ZPOOFQOATBKNCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237730   

TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237730(CHEMBL4074449)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human THP1 cells assessed as inhibition of LPS/BzATP-induced IL-1beta release preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237730(CHEMBL4074449)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human P2X7 receptor expressed in 1321N1 cells assessed as inhibition of agonist-induced calcium flux pretreated for 3 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed