BDBM50237726 CHEMBL4070819

SMILES N#C\N=C(\NCc1ccccc1)NCC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=AIIWKAJOBSWUBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237726   

TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237726(CHEMBL4070819)
Affinity DataIC50: 407nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237726(CHEMBL4070819)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human THP1 cells assessed as inhibition of LPS/BzATP-induced IL-1beta release preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed