BDBM50237576 CHEMBL4069492

SMILES Cc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1O

InChI Key InChIKey=ITGLACLFCZNNIB-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237576   

TargetP2Y purinoceptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237576(CHEMBL4069492)
Affinity DataIC50: 7.65E+3nMAssay Description:Antagonist activity at human P2Y1 receptor transfected in human 1321N1 cells assessed as inhibition of ADP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237576(CHEMBL4069492)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human P2Y12 receptor expressed in CHO cells assessed as inhibition of 2-MeSADP-induced beta-arrestin translocation preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237576(CHEMBL4069492)
Affinity DataIC50: 1.64E+4nMAssay Description:Antagonist activity at human P2Y2 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237576(CHEMBL4069492)
Affinity DataIC50: 746nMAssay Description:Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237576(CHEMBL4069492)
Affinity DataIC50: 4.75E+3nMAssay Description:Antagonist activity at human P2Y6 receptor transfected in human 1321N1 cells assessed as inhibition of UDP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed