BDBM50236711 CHEMBL4096394

SMILES Fc1ccc2c(-c3ccc(Cl)cc3)c(cnc2c1)S(=O)(=O)c1ccc(F)c(Cl)c1

InChI Key InChIKey=CWDRRLFHHJPBBQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236711   

TargetMetabotropic glutamate receptor 5(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236711(CHEMBL4096394)
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236711(CHEMBL4096394)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed