BDBM50236536 CHEMBL4102553

SMILES Oc1ccc(cc1)-c1cnc2[nH]cc(-c3ccc(cc3)-c3nnn[nH]3)c2c1

InChI Key InChIKey=QZIYOWZOZNSBGJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236536   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236536(CHEMBL4102553)
Affinity DataIC50: 172nMAssay Description:Inhibition of DYRK1B (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236536(CHEMBL4102553)
Affinity DataEC50:  8.50E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236536(CHEMBL4102553)
Affinity DataIC50: 416nMAssay Description:Inhibition of DYRK2 (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50236536(CHEMBL4102553)
Affinity DataIC50: 280nMAssay Description:Inhibition of DYRK1A (unknown origin) using woodtide as substrate after 10 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed