BDBM50236332 CHEMBL4072282

SMILES COc1ccccc1N1CCN(CCCNC(=O)Oc2ccc(cc2)-c2cccc(c2)C(N)=O)CC1

InChI Key InChIKey=ZUARVBUFFCRJPZ-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50236332   

TargetD(3) dopamine receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50236332(CHEMBL4072282)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50236332(CHEMBL4072282)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50236332(CHEMBL4072282)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human dopamine D2 receptor-short expressed in CHO-K1 cells assessed as reduction in adenylyl cyclase activator NKH 477 induced cA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50236332(CHEMBL4072282)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at recombinant human dopamine D3 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 30 mins by HTRF ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50236332(CHEMBL4072282)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human FAAH1 expressed in HEK293 cell membrane-enriched lysate using AMC arachidonyl amide as substrate preincubated for 50 mins followe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed