BDBM50236294 1-(2-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)ethyl)-3-(methylsulfonyl)urea::CHEMBL254569

SMILES CS(=O)(=O)NC(=O)NCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1

InChI Key InChIKey=AMPDDZBKINMTEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236294   

TargetC-X-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50236294(1-(2-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)eth...)
Affinity DataIC50: 640nMAssay Description:Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed