BDBM50235626 CHEMBL4075197
SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1cn(C)c2ccccc12
InChI Key InChIKey=ZNFRUVZPVKADAA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50235626
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of EED in human OCILY19 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 90nMAssay Description:Binding affinity to His tagged human EED (77 to 441 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair