BDBM50235583 CHEMBL4100781

SMILES COc1ccc(cc1)-n1c(nc2ccccc2c1=O)C(CC(C)C)NS(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=FVUSOJUPDSXANX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235583   

TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235583(CHEMBL4100781)
Affinity DataIC50: 97.4nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed