BDBM50235384 CHEMBL3900038

SMILES OC(=O)COC[C@H]1CC[C@@H](COC(=O)N(c2ccccc2)c2ccccc2)CC1

InChI Key InChIKey=GDJMTGQHKNDISN-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50235384   

TargetProstacyclin receptor(Rat)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235384(CHEMBL3900038)
Affinity DataEC50:  472nMAssay Description:Agonist activity at recombinant rat IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2019
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235384(CHEMBL3900038)
Affinity DataIC50: 54nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2019
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235384(CHEMBL3900038)
Affinity DataEC50:  54nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2019
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235384(CHEMBL3900038)
Affinity DataEC50:  1.71E+3nMAssay Description:Agonist activity at recombinant human DP1 receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2019
Entry Details Article
PubMed