BDBM50235299 CHEMBL4066397

SMILES Clc1ccccc1-n1ccc2ccc(NC(=O)NCC(=O)NCCCN[C@@H]3CCCN(C3)c3ncnc4[nH]ccc34)cc12

InChI Key InChIKey=SNPVMYPKFZRONU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235299   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235299(CHEMBL4066397)
Affinity DataIC50: 4nMAssay Description:Inhibition of DOT1L (2 to 416 residues) (unknown origin) using biotinylated nucleosomes as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50235299(CHEMBL4066397)
Affinity DataIC50: 4nMAssay Description:Inhibition of DOT1L (2 to 416 residues) (unknown origin) using biotinylated nucleosomes as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed