BDBM50234990 CHEMBL4062453

SMILES CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1

InChI Key InChIKey=CGECJCJUHCZZGO-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50234990   

TargetGlycogen synthase kinase-3 beta(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 91nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 370nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPKAPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 57nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 608nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetAurora kinase A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 20nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 441nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMed