BDBM50234661 CHEBI:76227::CHEMBL1619630

SMILES OC(=O)[C@@H]1CCn2c1ccc2C(=O)c1ccccc1

InChI Key InChIKey=OZWKMVRBQXNZKK-UHFFFAOYSA-N

Data  3 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50234661   

LigandPNGBDBM50234661(CHEMBL1619630 | CHEBI:76227)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RAC1/CDC42 in human ovarian cancer cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCell division control protein 42 homolog(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50234661(CHEMBL1619630 | CHEBI:76227)
Affinity DataEC50:  9.60E+4nMAssay Description:Inhibition of CDC42 in human HeLa cells pretreated for 1 hr followed by EGF stimulation for 2 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50234661(CHEMBL1619630 | CHEBI:76227)
Affinity DataEC50:  2.12E+5nMAssay Description:Inhibition of Rac1 in human HeLa cells pretreated for 1 hr followed by EGF stimulation for 2 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50234661(CHEMBL1619630 | CHEBI:76227)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50234661(CHEMBL1619630 | CHEBI:76227)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails
PubMed