BDBM50234234 CHEMBL4070493

SMILES CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc2ccccc2c1

InChI Key InChIKey=INRNCTNIWPOYHV-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50234234   

TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]5-HT uptake by SERT primary site (S1) (unknown origin) expressed in African green monkey COS1 cells after 10 mins by TopCount scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]5-HT uptake by SERT primary site (S1) (unknown origin) expressed in African green monkey COS1 cells after 10 mins by TopCount scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataEC50:  6.80E+4nMAssay Description:Inhibition of [3H]-S-citalopram dissociation from SERT allosteric modulator site (S2) (unknown origin) expressed in African green monkey COS1 cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataEC50:  6.80E+4nMAssay Description:Inhibition of [3H]-S-citalopram dissociation from SERT allosteric modulator site (S2) (unknown origin) expressed in African green monkey COS1 cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataEC50:  4.10E+4nMAssay Description:Inhibition of [3H]-S-citalopram dissociation from SERT allosteric modulator site (S2) (unknown origin) expressed in African green monkey COS1 cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234234(CHEMBL4070493)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]5-HT uptake by SERT primary site (S1) (unknown origin) expressed in African green monkey COS1 cells after 10 mins by TopCount scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed