BDBM50233900 CHEMBL4083954

SMILES O=C(NCc1cccc(OCCSc2nc[nH]n2)c1)c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=OXTBPBSHWBJLJN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233900   

TargetCollagenase 3(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50: 83nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50: 140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-2(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50: 140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed