BDBM50233805 CHEMBL4077922::US11021454, Compound Salvianolic acid C

SMILES OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c1ccc(O)c2oc(cc12)-c1ccc(O)c(O)c1

InChI Key InChIKey=GCJWPRRNLSHTRY-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233805   

TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataIC50: 8.26E+3nMAssay Description:11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataIC50: 6.87E+3nMAssay Description:12.1 Preparation of Reagents and Standard Solutions(1) Preparation of DPPH solution: accurately weigh the appropriate amount of DPPH, add MeOH and pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent

TargetSpike glycoprotein(SARS-CoV)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of spike glycoprotein S in SARS-CoV-2 pseudovirus infected human 293T/ACE2 cells assessed as inhibition of viral infection measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandPNGBDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataKi:  1.56E+4nMAssay Description:Displacement of [3H]2MeSADP from human P2Y12 expressed in U2OS cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed