BDBM50233798 CHEMBL398940::N-(2-aminoethyl)-1-aziridine-ethanamine::med.21724, Compound 7

SMILES NCCNCCN1CC1

InChI Key InChIKey=XJNAQZHMIAKQOK-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50233798   

TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of ACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataIC50: 5.70E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human recombinant ACE2 at 50 uM using (7Mca-Y-V-A- D -A-P- K(Knp) as a flurogenic substrate measured after 10 mins by fluorescence base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of SARS-COV2 pseudotyped virus binding to human ACE2 expressed in HEK293T cells using CPRG as substrate incubated for 3 hrs followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataKi:  4.59E+5nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataKi:  4.59E+5nMAssay Description:Binding affinity to ACE2 (unknown origin) at 10 uM assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50233798(N-(2-aminoethyl)-1-aziridine-ethanamine | CHEMBL39...)
Affinity DataKi:  4.59E+5nMAssay Description:Binding affinity to human recombinant ACE2 assessed as inhibition constant using fluorogenic peptide substrate VI incubated for 10 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed