BDBM50233092 8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1-butyl-1H-purine-2,6(3H,7H)-dione::CHEMBL253049

SMILES CCCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1cnn(Cc2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=WHFPIHBGEYJNRV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233092   

TargetAdenosine receptor A2b(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233092(8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ZM241385 from human A2B receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233092(8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233092(8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]-CPX from human A1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233092(8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [125I]-AB-MECA from human A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed