BDBM50233075 3-(3,4-dichlorophenyl)-N-((1s,4s)-4-((4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl)methyl)cyclohexyl)acrylamide::CHEMBL400698

SMILES Oc1ccc2[nH]cc(C3CCN(C[C@H]4CC[C@H](CC4)NC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1

InChI Key InChIKey=SVJJDCWBAXTWLW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233075   

TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50233075(3-(3,4-dichlorophenyl)-N-((1s,4s)-4-((4-(5-hydroxy...)
Affinity DataKi:  79nMAssay Description:Antagonist activity at human CCR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50233075(3-(3,4-dichlorophenyl)-N-((1s,4s)-4-((4-(5-hydroxy...)
Affinity DataKi:  79nMAssay Description:Inhibition of [125I]MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50233075(3-(3,4-dichlorophenyl)-N-((1s,4s)-4-((4-(5-hydroxy...)
Affinity DataKi:  79nMAssay Description:Inhibition of [125I]MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50233075(3-(3,4-dichlorophenyl)-N-((1s,4s)-4-((4-(5-hydroxy...)
Affinity DataKi:  126nMAssay Description:Inhibition of [125I]MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed