BDBM50233045 CHEMBL4091540

SMILES ONC(=O)CCCCN1c2ccccc2C(=N[C@@H](Cc2ccccc2)C1=O)c1ccccc1

InChI Key InChIKey=GMBOVOFMFHOGMM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233045   

TargetHistone deacetylase 6(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50233045(CHEMBL4091540)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human KDAC6 using FITC-labeled histone H4 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50233045(CHEMBL4091540)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of human KDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50233045(CHEMBL4091540)
Affinity DataIC50: 490nMAssay Description:Inhibition of human KDAC3 using FITC-labeled p53 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50233045(CHEMBL4091540)
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of human KDAC1 using substrate A after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50233045(CHEMBL4091540)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed