BDBM50232992 CHEMBL4073372

SMILES CC(C)(C)OC(=O)NCCCC[C@@H]1N=C(c2ccccc2)c2ccccc2N(CCCCC(=O)NO)C1=O

InChI Key InChIKey=BQCNBMZYCKJLND-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232992   

TargetHistone deacetylase 3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50232992(CHEMBL4073372)
Affinity DataIC50: 590nMAssay Description:Inhibition of human KDAC3 using FITC-labeled p53 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50232992(CHEMBL4073372)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human KDAC6 using FITC-labeled histone H4 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50232992(CHEMBL4073372)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human KDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50232992(CHEMBL4073372)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of human KDAC1 using substrate A after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50232992(CHEMBL4073372)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed