BDBM50232913 CHEMBL4103350

SMILES N[C@@H](CC(N)=O)C(=O)N1CCC(CC1)Nc1ccc2CN(Cc2c1)S(=O)(=O)c1ccc(O)cc1O

InChI Key InChIKey=UDNJJABYGHGSGZ-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50232913   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of recombinant human PDK1 in presence of E1 protein incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of recombinant human PDK3 in presence of E1 protein incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of recombinant human PDK1 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of recombinant human PDK3 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataKd:  22nMAssay Description:Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human PDK4 in presence of E1 protein incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
National Institute of Biological Science

Curated by ChEMBL
LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataIC50: 416nMAssay Description:Inhibition of recombinant human PDK4 in presence of E1 protein and PDC core E2/E3BP incubated for 10 mins by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed