BDBM50232890 CHEMBL4102677

SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])\C(=N/OC)C(=O)N6c7ccccc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]

InChI Key InChIKey=JIEFHNBYMOMHOJ-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50232890   

TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 214nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced rece...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced rece...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50232890(CHEMBL4102677)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]strychnine from recombinant human glycine receptor alpha 1 expressed in HEK293 cell membranes after 30 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed