BDBM50232502 (2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro[[1,-2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine hydrochloride::CHEMBL557542

SMILES C[C@@H]1N(CCn2c1nnc2C(F)(F)F)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=OEMLVLZERHBEJW-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50232502   

TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 88nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse DPP4 at 1 mg/kgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232502((2R)-4-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed