BDBM50232501 (2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6-dihydro[[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine hydrochloride::CHEMBL540888

SMILES N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1Cc1ccccc1F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=VVYNDQBBGPUYHW-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50232501   

TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232501((2R)-4-[8-(2-fluorobenzyl)-3-(trifluoromethyl)-5,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed