BDBM50232135 (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-2-cyano-3-(1H-indazol-4-yl)guanidine::CHEMBL3085384

SMILES CC(C)(C)c1ccc2[C@@H](CCc2c1)N\C(Nc1cccc2[nH]ncc12)=N\C#N

InChI Key InChIKey=DEGNPZKKRORGOM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232135   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50232135((R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-2-c...)Copy SMILESCopy InChI

Affinity DataIC50: 34nMAssay Description:Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL