BDBM50232125 1-(1H-Indazol-4-yl)-3-[4-(4-trifluoromethyl)piperidin-1-yl-indan-1-yl)-urea::CHEMBL401329

SMILES FC(F)(F)C1CCN(CC1)c1cccc2C(CCc12)NC(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=TZTRDENRXZLOMH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232125   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50232125(1-(1H-Indazol-4-yl)-3-[4-(4-trifluoromethyl)piperi...)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL