BDBM50231823 CHEMBL4080611::US11725000, Compound 61

SMILES COC(=O)c1ccc(cc1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=CTBGCKXPDXMUGQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231823   

LigandPNGBDBM50231823(CHEMBL4080611 | US11725000, Compound 61)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50231823(CHEMBL4080611 | US11725000, Compound 61)
Affinity DataEC50: <1.00E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails
US Patent