BDBM50231802 CHEMBL4078150::US11725000, Compound 48

SMILES Cc1ccc(cc1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=CPVFJDIGIVKEBO-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231802   

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
Peking University

Curated by ChEMBL

LigandBDBM50231802(CHEMBL4078150 | US11725000, Compound 48)Copy SMILESCopy InChI

Affinity DataEC50:  6.36E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/7/2019
Entry Details Article
Copy Entry DOIPubMed
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TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
Peking University

Curated by ChEMBL

LigandBDBM50231802(CHEMBL4078150 | US11725000, Compound 48)Copy SMILESCopy InChI

Affinity DataEC50: <1.00E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/21/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL