BDBM50231792 CHEMBL4100077::US11725000, Compound 120

SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccc(=O)n(Cc2cccc(c2)C#C)c1

InChI Key InChIKey=ZEAMKRDCAXMQDZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231792   

LigandPNGBDBM50231792(CHEMBL4100077 | US11725000, Compound 120)
Affinity DataEC50:  4.48E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50231792(CHEMBL4100077 | US11725000, Compound 120)
Affinity DataEC50:  5.01E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails
US Patent