BDBM50231597 CHEMBL4102409

SMILES CCCn1c(Oc2cccc(OC)c2)nc2nc([nH]c2c1=O)C1CCCC1

InChI Key InChIKey=YMYCBNUDQBLQGI-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50231597   

TargetAdenosine receptor A3(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231597(CHEMBL4102409)
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2019
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50231597(CHEMBL4102409)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human adenosine A1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50231597(CHEMBL4102409)
Affinity DataKi:  2.30nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2019
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50231597(CHEMBL4102409)
Affinity DataKi:  12nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50231597(CHEMBL4102409)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2019
Entry Details Article
PubMed