BDBM50229651 (S)-pyrrolidin-2-ylmethyl 4-((4-(4-cyano-2-methylphenyl)piperidin-1-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate::CHEMBL253021

SMILES Cc1cc(ccc1C1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC[C@@H]1CCCN1)C(=O)NO)C#N

InChI Key InChIKey=RMPKUSBLGZHQII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229651   

LigandPNGBDBM50229651((S)-pyrrolidin-2-ylmethyl 4-((4-(4-cyano-2-methylp...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229651((S)-pyrrolidin-2-ylmethyl 4-((4-(4-cyano-2-methylp...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50229651((S)-pyrrolidin-2-ylmethyl 4-((4-(4-cyano-2-methylp...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229651((S)-pyrrolidin-2-ylmethyl 4-((4-(4-cyano-2-methylp...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed