BDBM50229220 CHEMBL254744::N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamide

SMILES Cc1nc(sc1C(=O)NCc1ccc(NS(C)(=O)=O)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BIHNWTMNUQSVRZ-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50229220   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50229220(N-(4-(methylsulfonamido)benzyl)-4-methyl-2-(4-(tri...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse PPARgamma assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed