BDBM50229115 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-2-methylphenyl)(4-ethylpiperazin-1-yl)methanone::CHEMBL254893

SMILES CCN1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C

InChI Key InChIKey=JUFJPPYYAUZVAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229115   

TargetHigh affinity nerve growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50229115((5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed