BDBM50228837 2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitrile::2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitrile::CHEMBL272111

SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)C#N

InChI Key InChIKey=VFUHTVVDQYOCNI-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50228837   

TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataIC50: 26nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant FAAH expressed COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50228837(2-(3-biphenyl-4-yl-propionyl)-oxazole-5-carbonitri...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed