BDBM50228410 CHEMBL239535::diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidinophenyl)-ethanephosphonate

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(-[#6]-[#6](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)P(=O)([#8]-c2ccccc2)[#8]-c2ccccc2)cc1

InChI Key InChIKey=QYIHBHWLTWGXGY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228410   

TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228410(diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidino...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228410(diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidino...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228410(diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228410(diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228410(diphenyl 1-(benzyloxycarbonylamino)-2-(4-guanidino...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed