BDBM50227019 CHEMBL271673::sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

SMILES Nc1c(cc(Nc2ccc(Cl)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O

InChI Key InChIKey=MHSMKEQLFFWYOS-UHFFFAOYSA-M

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50227019   

TargetP2Y purinoceptor 2(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataIC50: 5.31E+3nMAssay Description:Antagonist activity at human recombinant P2Y2 receptor in 1321N1 cells assessed as inhibition of UTP-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataIC50: 3.03E+3nMAssay Description:Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) measured after 2 hrs by fluorescence based analys...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) incubated for 2 hrs in presence of staurosporine ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataKi:  4.81E+3nMAssay Description:Inhibition of rat ecto-5'-nucleotidase expressed in Sf9 cells by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 12(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataKi:  7.35E+3nMAssay Description:Displacement of [3H]PSB0413 from human platelet P2Y12 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataKi:  1.57E+4nMAssay Description:Inhibition of rat CD39 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed