BDBM50226441 2-amino-3-methyl-6-(2-(naphthalen-2-yl)ethyl)pyrimidin-4(3H)-one::CHEMBL237889

SMILES Cn1c(N)nc(CCc2ccc3ccccc3c2)cc1=O

InChI Key InChIKey=LTYRZHLAUJRMPD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226441   

TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226441(2-amino-3-methyl-6-(2-(naphthalen-2-yl)ethyl)pyrim...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226441(2-amino-3-methyl-6-(2-(naphthalen-2-yl)ethyl)pyrim...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of BACE1 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226441(2-amino-3-methyl-6-(2-(naphthalen-2-yl)ethyl)pyrim...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of BACE1 by IGEN assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed