BDBM50225736 4-(2-(2,4-dimethoxyphenyl)thiazol-4-yl)benzene-1,3-diol::CHEMBL236896

SMILES COc1ccc(-c2nc(cs2)-c2ccc(O)cc2O)c(OC)c1

InChI Key InChIKey=BASHTCWRHDHZNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225736   

TargetPolyphenol oxidase 2(White button mushroom)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50225736(4-(2-(2,4-dimethoxyphenyl)thiazol-4-yl)benzene-1,3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50225736(4-(2-(2,4-dimethoxyphenyl)thiazol-4-yl)benzene-1,3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed