BDBM50221967 (2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)-3-fluoro-pyrrolidin-1-yl)-N,N-dimethyl-4-oxo-butyramide::(2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-3-fluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide::CHEMBL237119

SMILES CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=YPGNHGMZLLVIHB-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50221967   

TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed