BDBM50221787 CHEMBL3216418

SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCc1nc(O)c(CCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C

InChI Key InChIKey=BRPKWONOOSMJCB-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221787   

TargetMu-type opioid receptor(Guinea pig)
National Institutes of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221787(CHEMBL3216418)
Affinity DataIC50: 1.30nMAssay Description:Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institutes of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221787(CHEMBL3216418)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for opioid receptor delta 1 agonism or antagonism in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institutes of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221787(CHEMBL3216418)
Affinity DataKi:  0.0420nMAssay Description:Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institutes of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221787(CHEMBL3216418)
Affinity DataKi:  13nMAssay Description:Compound was tested for binding affinity towards opioid receptor delta 1 by displacing [3H]DPDPE radioligand in rat brain P2 synaptosomes membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed