BDBM50220640 6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nicotinonitrile::CHEMBL249072

SMILES CC1CCN(CC1)c1cc(c(cn1)C#N)C(F)(F)F

InChI Key InChIKey=WGYGGXYUJRCLRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220640   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)
Affinity DataIC50: 136nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)
Affinity DataIC50: 73nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed