BDBM50220159 CHEMBL389589::N-[3'-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl-4-yl]sulfamide::N-[3'-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sulfamide

SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=GEMSMTTWZNDMSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220159   

TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220159(N-[3'-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sul...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220159(N-[3'-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sul...)
Affinity DataIC50: 20nMAssay Description:Inhibition of microtubule-stimulated recombinant Eg5 assessed as inhibition ATP hydrolysis by luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed