BDBM50218545 Nitraquazone

SMILES CCn1c(=O)n(-c2cccc(c2)[N+]([O-])=O)c2ccccc2c1=O

InChI Key InChIKey=GNWCRBFQZDJFTI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50218545   

LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2019
Entry Details Article
PubMed
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of phosphodiesterase 4 in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2019
Entry Details Article
PubMed
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of [3H]rolipram binding to rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 50nMAssay Description:Inhibitory potency against guinea pig ventricular phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory potency against guinea pig ventricular phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]rolipram from high affinity binding site (HARBS) in rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2018
Entry Details Article
PubMed